The Mouse Anti-CD54 Antibody from MyBioSource.com is a Mouse Monoclonal antibody. This antibody recognizes Human, and Porcine antigen. The Mouse Anti-CD54 Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Flow Cytometry, Immunohistochemistry - fixed, and Western Blot.
Description
Information: Human CD54 (ICAM-1) mediates cell adhesion by binding to the integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). CD54 expression on resting peripheral blood leukocytes is weak but is upregulated on activated T and B lymphocytes and on monocytes. Antibody 15.2 recognizes the D1 domain of the CD54 molecule of 90 kd. Antibody 15.2 inhibits CD54 binding to LFA-1